Found 19 matching trials
Targeting Cellular Senescence With Senolytics to Improve Skeletal Health in Older Humans
PHASE2To determine if senolytic drugs reduce senescent cell burden and reduce bon...
Location
Mayo Clinic in Rochester
Senolytic Therapy to Modulate the Progression of Alzheimer's Disease (SToMP-AD) Study
PHASE2The objective of the study is to determine the safety, feasibility, and eff...
Status
Active Not Recruiting
Location
Wake Forest Health Sciences
The Effect of Quercetin in Sarcoidosis
NAThe exact cause of the chronic lung disease sarcoidosis is still unknown. C...
Location
Maastricht University
Single Nuclei RNA-seq to Map Adipose Cellular Populations and Senescent Cells in Older Subjects
PHASE2All participants will undergo baseline biopsies of subcutaneous abdominal a...
Location
Cedars Sinai Medical Center
Role of Neutrophils and Electro-bioluminescence in the Rehabilitation
PHASE1The clinical study is to find out the effect of a course of immunomodulator...
Hematopoietic Stem Cell Transplant Survivors Study
PHASE1The investigators hope to find the proof of principle concept from this pil...
Location
Mayo Clinic in Rochester
Serum Concentration of Endogenous Estrogens and Sirtuin-1 After Administration of Atorvastatin and Quercetin:
NAChronic coronary syndrome (CCS) is the leading cause of death in women in t...
Location
INCOR- Heart Institute
Biological Effects of Quercetin in COPD Phase II
PHASE2This study determines whether quercetin supplementation reduces the inflamm...
Location
Nathaniel Marchetti
Advancing Niacin by Inhibiting Flushing (ANTI-FLUSH)
PHASE4Niacin, or vitamin B3, is known to improve cholesterol disorders and is the...
Location
CTRC Univ. of Penn - Andrew Mutch Bldg., 4th floor
ALSENLITE: Senolytics for Alzheimer's Disease
PHASE1This study is being done to evaluate the safety and feasibility of using Da...
Status
Active Not Recruiting
Location
Mayo Clinic in Rochester